Spironolactone (Spironolactone)

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Brand Name: Spironolactone

Generic Name: Spironolactone

Manufacturer/Agent: Metro Pharma

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Formulation: tabs

Strength: 25mg

Pack size: 28

Trade Price: KES 380.00

Retail Price: @ KES 18.10

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Class: Potassium-sparing Diuretics (Cardiovascular drugs)

Mechanism of Action:

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Synonym: Spirolactone

Molecular Formulae: C24H32O4S = 416.6

Precautions: Hyperkalaemia, addisons disease, pregnancy and lactation. hyponatraemia.

Indications/Uses: Oedema associated with congestive heart failure, cirrhosis or nephrotic syndrome; usual dose 100-200mg daily, with meals.

Interactions: Decreased effect: nsaids. increased risk of hyperkalamia with potassium supplements. may increase effect of digoxin.

Side Effects: Gastro-intestinal disturbances. impotence. gynaecomastia. fatigue. rash. menstrual irregularities. headache. confusion.

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