Epilim (Sodium Valproate)

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Brand Name: Epilim

Generic Name: Sodium Valproate

Manufacturer/Agent: Sanofi-aventis

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Formulation: syp

Strength: 300ml

Pack size: 1

Trade Price: KES 1,195.00

Retail Price: @ KES 1,593.33

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Class: Antiepileptics (CNS agents)

Mechanism of Action:

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Synonym: Valproic Acid Sodium Salt

Molecular Formulae: C8H15NAO2 = 166.2

Precautions: Liver disease. risk of teratogenicity. porphyria.

Indications/Uses: Gaba agonist used in absence seizures, mixed seizures; 600mg in divided doses.

Interactions: Decreased effect: carbamazepine, phenytoin, lamotrigine. increased effect: clonazepam, macrolides, isoniazid.

Side Effects: Mild gastro-intestinal and cns disturbances; nausea, drowsiness, headache. rash. hair loss. disorders of blood clotting. weakness. blurred vision.

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