Myleran (Busulphan)

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Brand Name: Myleran

Generic Name: Busulphan

Manufacturer/Agent: Glaxosmithkline Pharma

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Formulation: tabs

Strength: 2mg

Pack size: 100

Trade Price: KES 5,288.40

Retail Price: @ KES 70.51

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Class: Alkylating Cytotoxic Drugs (Oncology & immunosuppression drugs)

Mechanism of Action:

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Synonym: Busulfan

Molecular Formulae: C6H14O6S2 = 246.3

Precautions: Hypersensitivity. gout. porphyria.

Indications/Uses: Myeloid leukaemia 60mcg/kg qid, 16 doses.

Interactions: Pulmonary toxicity increased by itraconazole

Side Effects: Bone marrow depression. hyperuricaemia. gastro-intestinal upset. hyperpigmentation. weakness. anorexia. broncopulmonary dysplasia.

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