Brand Name: Nogluc
Generic Name: Glibenclamide
Manufacturer/Agent: Cosmos Ltd
Pack size: 28
Trade Price: KES 75.00
Retail Price: @ KES 3.57
Class: Sulphonylureas (Endocrine system drugs)
Mechanism of Action: Stimulate insulin production, and on long-term use may have extrapancreatic effect. only useful when some beta-cell activity is intact.
Molecular Formulae: C23H28ClN3O5S = 494.0
Precautions: Severe renal or hepatic impairment. ketoacidosis. porphyria. pregnancy.
Indications/Uses: Non insulin-dependent diabetes; 2.5-15 mg daily.
Interactions: Sulphonamides, salicylates, mao inhibitors, oral anticoagulants, aspirin, alcohol, rifampicin may enhance effect.
Side Effects: Skin rashes. gastro-intestinal upset.