Phyllocontin (Aminophylline)

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Brand Name: Phyllocontin

Generic Name: Aminophylline

Manufacturer/Agent: Mundipharma/napp

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Formulation: tabs

Strength: 225mg

Pack size: 56

Trade Price: KES 855.00

Retail Price: @ KES 20.50

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Class: Xanthines (Respiratory system drugs)

Mechanism of Action:

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Synonym:

Molecular Formulae: (C7H8N4O2)2.C2H4(NH2)2 = 420.4

Precautions: Caution in peptic ulcer, hyperthyroidism, hypertension and congestive heart failure.

Indications/Uses: Acute asthma attacks by slow iv 5-6mg/kg. acute bronchospasm orally 300mg 3-4 times a day.

Interactions: Quinolones (risk of convulsions). fluvoxamine, azole antifungals, ticlopidine, calcium channel blockers, cimetidine increase effect. ritonavir reduces effect.

Side Effects: Tachycardia. nausea. gastro-intestinal distress. arrhythmias.

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