Zocor (Simvastatin)
Brand Name: Zocor
Generic Name: Simvastatin
Manufacturer/Agent: Merck Sharpe
Formulation: tabs
Strength: 20mg
Pack size: 28
Trade Price: KES 4,286.00
Retail Price: @ KES 204.10
Class: Statins (Cardiovascular drugs)
Mechanism of Action:
Synonym: Velastatin
Molecular Formulae: C25H38O5 = 469.4
Precautions: Hypersensitivity. pregnancy. porphyria.
Indications/Uses: Hypercholesterolaemia 10mg nocte.
Interactions: Substrate of cyp3a3/4. inducers eg rifampicin decrease effect while inhibitors eg ketoconazole increase effect of saquinavir
Side Effects: Alopecia. gastro-intestinal disturbances. reversible myositis. hypersensitivity reactions. anaemia. dizziness. peripheral neuropathy. jaundice. hepatitis. paraesthesia.