Fortovase (Saquinavir)
Brand Name: Fortovase
Generic Name: Saquinavir
Manufacturer/Agent: Roche Pdts Ltd
Formulation: caps
Strength: 200mg
Pack size: 180
Trade Price: KES 15,900.00
Retail Price: @ KES 0.00
Class: Antiretrovirals (Anti-infectives)
Mechanism of Action:
Synonym:
Molecular Formulae: C38H50N6O5.CH4O3S = 766.9
Precautions: Pregnancy. severe hepatic dysfunction. caution in diabetes.
Indications/Uses: Protease inhibitor used with other agents in treatment of hiv infection; 600mg tid (hard gelation capsules), 1200mg tds (soft gelatin capsules). should be taken within 2 hrs of a meal.
Interactions: Substrate of cyp3a3/4. inducers eg rifampicin decrease effect while inhibitors eg ketoconazole increase effect of saquinavir
Side Effects: Steven-johnson syndrome. nephrolithiasis. pancreatitis. ulceration of the mucous membrane. depression. peripheral neuropathy. nausea.