Fortovase (Saquinavir)


Brand Name: Fortovase

Generic Name: Saquinavir

Manufacturer/Agent: Roche Pdts Ltd


Formulation: caps

Strength: 200mg

Pack size: 180

Trade Price: KES 15,900.00

Retail Price: @ KES 0.00


Class: Antiretrovirals (Anti-infectives)

Mechanism of Action:


Synonym:

Molecular Formulae: C38H50N6O5.CH4O3S = 766.9

Precautions: Pregnancy. severe hepatic dysfunction. caution in diabetes.

Indications/Uses: Protease inhibitor used with other agents in treatment of hiv infection; 600mg tid (hard gelation capsules), 1200mg tds (soft gelatin capsules). should be taken within 2 hrs of a meal.

Interactions: Substrate of cyp3a3/4. inducers eg rifampicin decrease effect while inhibitors eg ketoconazole increase effect of saquinavir

Side Effects: Steven-johnson syndrome. nephrolithiasis. pancreatitis. ulceration of the mucous membrane. depression. peripheral neuropathy. nausea.