Roaccutane (Isotrenitoin)
Brand Name: Roaccutane
Generic Name: Isotrenitoin
Manufacturer/Agent: Roche Pdts Ltd
Formulation: caps
Strength: 20mg
Pack size: 30
Trade Price: KES 5,916.00
Retail Price: @ KES 262.93
Class: Misc. Agents (Misc. drugs)
Mechanism of Action:
Synonym:
Molecular Formulae:
Precautions: Teratogenic, not for use in pregnancy. lactation. renal or hepatic impairment. severe hyperlipidaemia. hypervitaminosis a. hypersensitivity. use of tetracycline
Indications/Uses: Reduces the activity and size of sebaceous glands in severe acne. dose 0.5mg/kg initially, once daily with meals, to a maximum of 1mk/kg for about 4 weeks.
Interactions: Vitamin a. tetracyclines may increase risk of raised intracranial pressure.
Side Effects: Dryness of skin and mucous membranes. epistasis, hoarseness of voice. may worsen acne at start of use. dryness of eyes may lead to conjuctivitis. gastro-intestinal upsets.