Leponex (Clozapine)


Brand Name: Leponex

Generic Name: Clozapine

Manufacturer/Agent: Novartis Pharma


Formulation: tabs

Strength: 100mg

Pack size: 50

Trade Price: KES 8,371.00

Retail Price: @ KES 223.23


Class: Antipsychotics (CNS agents)

Mechanism of Action:


Synonym:

Molecular Formulae: C18H19ClN4 = 326.8

Precautions: Alcoholic or toxic psychosis. bone marrow depression. uncontrolled epilepsy. severe renal failure.

Indications/Uses: An atypical antipyschotropic used in schizophrenia in patients who don't respond to classical agents.

Interactions: Increases the effect of mao inhibitors. higher risk of toxicity when used together with other bone marrow suppressants.

Side Effects: Reversible netropenia. agranulocytosis may be severe. extrapyramidal events. tachycardia. ordhostatic hypotension.