Amphotericin B
Synonym : Amphotericin
Molecular Formulae: : C47H73NO17 = 924.1
Precautions : Toxicity common when given parenterally. caution in renal impairment. pregnancy and lactation.
Indications/Uses: Systemic fungal infections; iv max 50mg/day over 2-6 hrs
Interactions : Digoxin (increased toxicity) ciclosporin (nephrotoxicity). corticosteroids (hypokalaemia).
Side Effects : Nausea. anorexia. epigastric pain. vomiting. fever. muscle and joints pains. anaemia. hypokalaemia. hypomagnesia. renal toxicity.
Brands with Amphotericin B :
Amphoterin
Amphotin
Amphotret
Fungizone
Photericin B
Tericin
Tericin