Arpimune (Cyclosporin)

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Brand Name: Arpimune

Generic Name: Cyclosporin

Manufacturer/Agent: Rpg Life Sciences

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Formulation: tabs

Strength: 100mg

Pack size: 50

Trade Price: KES 12,914.00

Retail Price: @ KES 344.37

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Class: Anticancer/immunosuppressants: Other (Oncology & immunosuppression drugs)

Mechanism of Action:

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Synonym: Ciclosporin

Molecular Formulae: C62H111N11O12 = 1202.6

Precautions: Use with aminoglycosides.

Indications/Uses: With corticosteroids for prophylaxis and treatment of graft rejection; 14-18mg/kg.

Interactions: Substrate of cyp3a3/4. inducers eg rifampicin decrease effect while inhibitors eg ketoconazole increase effect of saquinavir

Side Effects: Raised serum creatinine and urea. fatigue. gingival hypertrophy. gastro-intestinal upset. burning sensation . renal toxicity. hypertension. hirsutism. tremor.

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