Arpimune (Cyclosporin)
Brand Name: Arpimune
Generic Name: Cyclosporin
Manufacturer/Agent: Rpg Life Sciences
Formulation: caps
Strength: 50mg
Pack size: 50
Trade Price: KES 5,500.00
Retail Price: @ KES 146.67
Class: Anticancer/immunosuppressants: Other (Oncology & immunosuppression drugs)
Mechanism of Action:
Synonym: Ciclosporin
Molecular Formulae: C62H111N11O12 = 1202.6
Precautions: Use with aminoglycosides.
Indications/Uses: With corticosteroids for prophylaxis and treatment of graft rejection; 14-18mg/kg.
Interactions: Substrate of cyp3a3/4. inducers eg rifampicin decrease effect while inhibitors eg ketoconazole increase effect of saquinavir
Side Effects: Raised serum creatinine and urea. fatigue. gingival hypertrophy. gastro-intestinal upset. burning sensation . renal toxicity. hypertension. hirsutism. tremor.